Structure of PDB 1mzv Chain A

Receptor sequence
>1mzvA (length=216) Species: 5689 (Leishmania tarentolae) [Search protein sequence]
SLKEIGPNSLLLEDSHSLSQLLKKNYRWYSPIFSPRNVPRFADVSSITES
PETLKAIRDFLVERYRTMSPAPTHILGFDARGFLFGPMIAVELGIPFVLM
RKADKNAGLLIRSEPYEKEYKEAAPEVMTIRHGSIGKNSRVVLIDDVLAT
GGTALSGLQLVEASGAEVVEMVSILTIPFLKAAERIHSTAGGRYKNVRFI
GLLSEDVLTEANCGDL
3D structure
PDB1mzv Crystal structure of adenine phosphoribosyltransferase from Leishmania tarentolae: potential implications for APRT catalytic mechanism.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R82 E120
Catalytic site (residue number reindexed from 1) R81 E119
Enzyme Commision number 2.4.2.7: adenine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A R37 F42 A43 R82 D146 D147 V148 A150 T151 G152 T154 R36 F41 A42 R81 D145 D146 V147 A149 T150 G151 T153
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003999 adenine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1mzv, PDBe:1mzv, PDBj:1mzv
PDBsum1mzv
PubMed14726202
UniProtO77103

[Back to BioLiP]