Structure of PDB 1mwj Chain A

Receptor sequence
>1mwjA (length=165) Species: 562 (Escherichia coli) [Search protein sequence]
MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDRQ
LKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQ
PQALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLE
KLVEAYRELDQALVV
3D structure
PDB1mwj Crystal Structure of a thwarted mismatch glycosylase DNA repair complex
ChainA
Resolution2.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N18 P29
Catalytic site (residue number reindexed from 1) N18 P29
Enzyme Commision number 3.2.2.28: double-stranded uracil-DNA glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A G143 R146 G143 R146
Gene Ontology
Molecular Function
GO:0000700 mismatch base pair DNA N-glycosylase activity
GO:0003677 DNA binding
GO:0004844 uracil DNA N-glycosylase activity
GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity
GO:0016787 hydrolase activity
GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity
Biological Process
GO:0006281 DNA repair
GO:0006285 base-excision repair, AP site formation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mwj, PDBe:1mwj, PDBj:1mwj
PDBsum1mwj
PubMed10581234
UniProtP0A9H1|MUG_ECOLI G/U mismatch-specific DNA glycosylase (Gene Name=mug)

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