Structure of PDB 1mvy Chain A

Receptor sequence

>1mvyA (length=628) Species: 489 (Neisseria polysaccharea)

SPNSQYLKTRILDIYTPEQRAGIEKSEDWRQFSRRMDTHFPKLMNELDSV
YGNNEALLPMLEMLLAQAWQSYSQRNSSLKDIDIARENNPDWILSNKQVG
GVCYVDLFAGDLKGLKDKIPYFQELGLTYLYLMPLFKCPEGKSDGGYAVS
SYRDVNPALGTIGDLREVIAALHEAGISAVVDFIFNHTSNEHEWAQRCAA
GDPLFDNFYYIFPDRRMPDQYDRTLREIFPDQHPGGFSQLEDGRWVWTTF
NSFQWDLNYSNPWVFRAMAGEMLFLANLGVDILRMDAVAFIWKQMGTSCE
NLPQAHALIRAFNAVMRIAAPAVFFKSQAIVHPDQVVQYIGQDECQIGYN
PLQMALLWNTLATREVNLLHQALTYRHNLPEHTAWVNYVRSHDDIGWTFA
DEDAAYLGISGYDHRQFLNRFFVNRFDGSFARGVPFQYNPSTGDCRVSGT
AAALVGLAQDDPHAVDRIKLLYSIALSTGGLPLIYLGDEVGTLNDDDWSQ
DSNKSDDSRWAHRPRYNEALYAQRNDPSTAAGQIYQGLRHMIAVRQSNPR
FDGGRLVTFNTNNKHIIGYIRNNALLAFGNFSEYPQTVTAHTLQAMPFKA
HDLIGGKTVSLNQDLTLQPYQVMWLEIA

3D structure

• PDB: 1mvy Oligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITY
• Chain: A
• Resolution: 2.0 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): D182 R284 D286 Q328 H392 D393
• Catalytic site (residue number reindexed from 1): D182 R284 D286 Q328 H392 D393
• Enzyme Commision number: 2.4.1.4: amylosucrase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	A	H414 F417 F426	H414 F417 F426
BS02	GLC	A	T363 E365	T363 E365
BS03	GLC	A	R364 E583	R364 E583
BS04	GLC	A	F559 N560	F559 N560

Gene Ontology

Molecular Function

• GO:0016757 glycosyltransferase activity
• GO:0047669 amylosucrase activity

Biological Process

• GO:0005975 carbohydrate metabolic process

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:1mvy, PDBe:1mvy, PDBj:1mvy
• PDBsum: 1mvy
• PubMed: 12364331
• UniProt: Q9ZEU2|AMYS_NEIPO Amylosucrase (Gene Name=ams)