Structure of PDB 1mv9 Chain A

Receptor sequence
>1mv9A (length=214) Species: 9606 (Homo sapiens) [Search protein sequence]
DMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDD
QVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIF
DRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKV
YASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
IDTFLMEMLEAPHQ
3D structure
PDB1mv9 Molecular Recognition of Agonist Ligands by RXRs
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V280 K284 Q297 V298 L301 R302 T449 F450 E453 V34 K38 Q51 V52 L55 R56 T203 F204 E207
BS02 HXA A I268 A271 A272 Q275 L309 I310 F313 R316 L326 A327 V342 I345 C432 L436 I22 A25 A26 Q29 L63 I64 F67 R70 L80 A81 V96 I99 C186 L190
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:1mv9, PDBe:1mv9, PDBj:1mv9
PDBsum1mv9
PubMed11981034
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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