Structure of PDB 1mux Chain A

Receptor sequence

>1muxA (length=148) Species: 8355 (Xenopus laevis)

ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD
MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI
SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

3D structure

• PDB: 1mux Solution structure of calmodulin-W-7 complex: the basis of diversity in molecular recognition.
• Chain: A
• Resolution: N/A

Enzymatic activity

• Catalytic site (original residue number in PDB): V35
• Catalytic site (residue number reindexed from 1): V35

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	A	D20 D22 D24 T26 E31	D20 D22 D24 T26 E31
BS02	CA	A	D56 D58 N60 T62 E67	D56 D58 N60 T62 E67
BS03	CA	A	D93 D95 N97 Y99 E104	D93 D95 N97 Y99 E104
BS04	CA	A	D129 D131 G132 D133 E140	D129 D131 G132 D133 E140
BS05	WW7	A	F19 L32 L39 M51 M72	F19 L32 L39 M51 M72
BS06	WW7	A	E84 E87 F92 L105 F141 M144 M145	E84 E87 F92 L105 F141 M144 M145

Gene Ontology

Molecular Function

• GO:0005102 signaling receptor binding
• GO:0005509 calcium ion binding
• GO:0030234 enzyme regulator activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:1mux, PDBe:1mux, PDBj:1mux
• PDBsum: 1mux
• PubMed: 9514729
• UniProt: P0DP33|CALM1_XENLA Calmodulin-1 (Gene Name=calm1)