Structure of PDB 1mu5 Chain A

Receptor sequence
>1mu5A (length=460) Species: 2286 (Saccharolobus shibatae) [Search protein sequence]
LSPAEFFKRNPELAGFPNPARALYQTVRELIENSLDATDVHGILPNIKIT
IDLIDDARQIYKVNVVDNGIGIPPQEVPNAFGRVLYSKYVNRQTRGMYGL
GVKAAVLYSQMHQDKPIEIETSPVNSKRIYTFKLKIDINKNEPIIVERGS
VENTRGFHGTSVAISIPGDWPKAKSRIYEYIKRTYIITPYAEFIFKDPEG
NVTYYPRLTNKIPKPPQEVKPHPYGVDREEIKILINNLKRDYTIKEFLVN
EFQSIGDTTADKILELAGLKPNKKVKNLTEEEITRLVETFKKYEDFRSPS
ADSLSVIGEDLIELGLKKIFNPDFAASITRKPKAYQGHPFIVEAGVAFGG
SIPVGEEPIVLRYANKIPLIYDEKSDVIWKVVEELDWKRYGIESDQYQMV
VMVHLCSTKIPYKSAGKESIAEVEDIEKEIKNALMEVARKLKQYLSEKRK
EQEAKKKLLA
3D structure
PDB1mu5 Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E393 L395 E383 L385
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:1mu5, PDBe:1mu5, PDBj:1mu5
PDBsum1mu5
PubMed12505993
UniProtO05207|TOP6B_SACSH Type 2 DNA topoisomerase 6 subunit B (Gene Name=top6B)

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