Structure of PDB 1mnd Chain A

Receptor sequence
>1mndA (length=641) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
NPIHDRTSDYHKYLKVKQTVSDKRYIWYNPDPDERDSYECGEIVSETSDS
FTFKTVQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRVRYN
QDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAISDV
AYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGVLEQQILQAN
PILEAFGNAKTTRNNNSSRFGKFIEIQFNNAGFISGASIQSYLLEKSRVV
FQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGCVDIKGVS
DEDEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKGAGEGAVL
KDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVEKSSSSRD
ALVKALYGRLFLWLVKKINNVLCSRAAYFIGVLDISGFEIFKVNSFEQLC
INYTNEKLQQFFNHHMDSQATIDLIDGRQPPGILALLDEQSVFPNATDNT
LITKLHSHFSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPL
QQDLELCFKDSSDNVVTKLFNDPNIASRFITVAAQYKEQLASLMATLETT
NPHFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEIRITRK
3D structure
PDB1mnd X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S170 G171 T175 N214 S217 S218 G437 E439
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T186 S237 T175 S218
BS02 ALF A S181 K185 S236 S237 G457 S170 K174 S217 S218 G437
BS03 ADP A N127 P128 F129 G182 G184 K185 T186 N233 N116 P117 F118 G171 G173 K174 T175 N214
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1mnd, PDBe:1mnd, PDBj:1mnd
PDBsum1mnd
PubMed7619795
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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