Structure of PDB 1mmd Chain A

Receptor sequence
>1mmdA (length=743) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPDERDSYECGE
IVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPA
VFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEV
APHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG
RNQAGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNNAGFIS
GASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESF
NYLNQSGCVDIKGVSDEDEFKITRQAMDIVGFSQEEQMSIFKIIAGILHL
GNIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDL
VAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCSERAAYFIGVLD
ISGFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKVEQEEYLKEKINLDSQ
ATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEP
RFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKL
FNDPNIASRAFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAK
LEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDA
EDSQKATDAVLKHLNIDPEQYRFGITKIFFRAGQLARIEEARE
3D structure
PDB1mmd X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S180 G181 T185 N229 S232 S233 G453 E455
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T186 S237 T185 S233
BS02 ADP A N127 P128 R131 S181 G182 G184 K185 T186 E187 N233 N126 P127 R130 S180 G181 G183 K184 T185 E186 N229
BS03 BEF A S181 G182 K185 N233 S236 S237 S180 G181 K184 N229 S232 S233
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1mmd, PDBe:1mmd, PDBj:1mmd
PDBsum1mmd
PubMed7619795
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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