Structure of PDB 1mjw Chain A

Receptor sequence
>1mjwA (length=175) Species: 562 (Escherichia coli) [Search protein sequence]
SLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVNRFMSTAMF
YPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAG
EDAKLVAVPHSKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWV
KVEGWENAEAAKAEIVASFERAKNK
3D structure
PDB1mjw Three-dimensional structures of mutant forms of E. coli inorganic pyrophosphatase with Asp-->Asn single substitution in positions 42, 65, 70, and 97.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.1: inorganic diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A K29 R43 Y141 K142 K29 R43 Y141 K142
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004427 inorganic diphosphate phosphatase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050355 inorganic triphosphate phosphatase activity
Biological Process
GO:0006796 phosphate-containing compound metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:1mjw, PDBe:1mjw, PDBj:1mjw
PDBsum1mjw
PubMed9668207
UniProtP0A7A9|IPYR_ECOLI Inorganic pyrophosphatase (Gene Name=ppa)

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