Structure of PDB 1mje Chain A

Receptor sequence
>1mjeA (length=600) Species: 10090 (Mus musculus) [Search protein sequence]
KDLMSSLQSARDLQDMRIKNKERRHLRLQPGSLYLTKSSTLPRISLQAAV
GDRAPSACSPKQLYIYGVSKECINVNSKNAEYFQFDIQDHFGKEDLCAGK
GFQLADGGWLIPSNDGKAGKEEFYRALCDTPGVDPKLISSIWVANHYRWI
VWKLAAMEFAFPKEFANRCLNPERVLLQLKYRYDVEIDNSRRSALKKILE
RDDTAAKTLVLCISDIVDTIELTDGWYAVRAQLDPPLMALVKSGKLTVGQ
KIITQGAELVGSPDACAPLEAPDSLRLKISANSTRPARWHSRLGFFRDPR
PFPLPLSSLFSDGGNVGCVDIIVQRVYPLQWVEKTVSGLYIFRSEREEEK
EALRFAEAQQKKLEALFTKVHTLSRDVTTVWKLRVTSYKKKEKSALLSIW
RPSSDLSSLLTEGKRYRIYHLAVSKSKSKFERPSIQLTATKRTQYQQLPV
SSETLLQVYQPRESLHFSRLSDPAFQPPCSEVDVVGVVVSVVKPIGLAPL
VYLSDECLNLLVVKFGIDLNEDIKPRVLIAASNLQCQPESTSGVPTLFAC
HFSIFSASPKEAYFQEKVNNLKHAIENIDTFYKEAEKKLIHVLEGDSPKW
3D structure
PDB1mje BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A F2762 K2891 S2907 W2909 R2910 F2939 Q2945 T2947 G3005 L3006 A3007 Q3046 F3057 C3059 H3060 F342 K382 S398 W400 R401 F430 Q436 T438 G496 L497 A498 Q537 F548 C550 H551
Gene Ontology
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair

View graph for
Biological Process
External links
PDB RCSB:1mje, PDBe:1mje, PDBj:1mje
PDBsum1mje
PubMed12228710
UniProtP97929|BRCA2_MOUSE Breast cancer type 2 susceptibility protein homolog (Gene Name=Brca2)

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