Structure of PDB 1miw Chain A

Receptor sequence
>1miwA (length=395) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
MKPPFQEALGIIQQLKQHGYDAYFVGGAVRDLLLGRPIGDVDIATSALPE
DVMAIFPKTIDVGSKHGTVVVVHKGKAYEVTTFKTDGSVTFVRSLEEDLK
RRDFTMNAIAMDEYGTIIDPFGGREAIRRRIIRTVGEAEKRFREDALRMM
RAVRFVSELGFALAPDTEQAIVQNAPLLAHISVERMTMEMEKLLGGPFAA
RALPLLAETGLNAYLPGLAGKEKQLRLAAAYRWPWLAAREERWALLCHAL
GVQESRPFLRAWKLPNKVVDEAGAILTALADIPRPEAWTNEQLFSAGLER
ALSVETVRAAFTGAPPGPWHEKLRRRFASLPIKTKGELAVNGKDVIEWVG
KPAGPWVKEALDAIWRAVVNGEVENEKERIYAWLMERNRTREKNC
3D structure
PDB1miw Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.72: CCA tRNA nucleotidyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G27 R30 R111 D112 N116 R157 R160 R163 G27 R30 R102 D103 N107 R148 R151 R154
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004810 CCA tRNA nucleotidyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0042245 RNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1miw, PDBe:1miw, PDBj:1miw
PDBsum1miw
PubMed12526808
UniProtQ7SIB1|CCA_GEOSE CCA-adding enzyme (Gene Name=cca)

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