Structure of PDB 1mh5 Chain A

Receptor sequence
>1mh5A (length=197) Species: 10090 (Mus musculus) [Search protein sequence]
DIVMTQAAPSVSVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQ
LLIYRMSNLASGVPDRFSGSGSGTAFTLRISRVEAEDVGVYYCLQHLEYP
FTFGAGTKLELKRADAAPTVSIFPPASVVCFLNNFYPKDINVKWKIDGSE
RQNGVLNSWTDQDSKDSTYSMSSTLTLTKRHNSYTCEATSPIVKSFN
3D structure
PDB1mh5 High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HAL A H27D Y32 L89 H91 L92 Y94 F96 H31 Y37 L94 H96 L97 Y99 F101 PDBbind-CN: -logKd/Ki=9.21,Kd=0.61nM
Gene Ontology
Biological Process
GO:0030183 B cell differentiation
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1mh5, PDBe:1mh5, PDBj:1mh5
PDBsum1mh5
PubMed12948492
UniProtP01837|IGKC_MOUSE Immunoglobulin kappa constant (Gene Name=Igkc)

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