Structure of PDB 1meg Chain A

Receptor sequence
>1megA (length=216) Species: 3649 (Carica papaya) [Search protein sequence]
LPENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSE
QELVDCERRSHGCKGGYPPYALEYVAKNGIHLRSKYPYKAKQGTCRAKQV
GGPIVKTSGVGRVQPNNEGNLLNAIAKQPVSVVVESKGRPFQLYKGGIFE
GPCGTKVEHAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAPGNS
PGVCGLYKSSYYPTKN
3D structure
PDB1meg Crystal structure of a caricain D158E mutant in complex with E-64.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q19 C25 H159 N179
Catalytic site (residue number reindexed from 1) Q19 C25 H159 N179
Enzyme Commision number 3.4.22.30: caricain.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 E64 A Q19 G23 C25 W26 G65 G66 Y67 V133 E158 H159 Q19 G23 C25 W26 G65 G66 Y67 V133 E158 H159
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1meg, PDBe:1meg, PDBj:1meg
PDBsum1meg
PubMed8769310
UniProtP10056|PAPA3_CARPA Caricain

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