Structure of PDB 1mdz Chain A

Receptor sequence
>1mdzA (length=364) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
DFLPFSRPAMGAEELAAVKTVLDSGWITTGPKNQELEAAFCRLTGNQYAV
AVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMIVLLGANPVMVDV
DRDTLMVTPEHIEAAITPQTKAIIPVHYAGAPADLDAIYALGERYGIPVI
EDAAHATGTSYKGRHIGARGTAIFSFHAIKNITCAEGGIVVTDNPQFADK
LRSLKFHGLGVDQAEVLAPGYKYNLPDLNAAIALAQLQKLDALNARRAAI
AAQYHQAMADLPFQPLSLPSWEHIHAWHLFIIRVDEARCGITRDALMASL
KTKGIGTGLHFRAAHTQKYYRERFPTLTLPDTEWNSERICSLPLFPDMTE
SDFDRVITALHQIA
3D structure
PDB1mdz Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: A 4-amino-4-deoxy-L-arabinose lipopolysaccharide modifying enzyme
ChainA
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.87: UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 DCS A A63 T64 W89 D160 A162 H163 S183 H185 I187 K188 H329 F330 A55 T56 W81 D152 A154 H155 S175 H177 I179 K180 H310 F311
BS02 PLP A A63 T64 W89 D160 A162 H163 S183 K188 A55 T56 W81 D152 A154 H155 S175 K180
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0099620 UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009245 lipid A biosynthetic process
GO:0046493 lipid A metabolic process
GO:0046677 response to antibiotic

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1mdz, PDBe:1mdz, PDBj:1mdz
PDBsum1mdz
PubMed12429098
UniProtQ8ZNF3|ARNB_SALTY UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (Gene Name=arnB)

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