Structure of PDB 1mb9 Chain A

Receptor sequence
>1mb9A (length=485) Species: 1901 (Streptomyces clavuligerus) [Search protein sequence]
PVLPAAFGFLASARTGAPGPVFATRGSHTDIDTPQGERSLAATLVHAPSV
APDRAVARSLTGAPTTAVLAGEIYNRDELLSVLPAGPAPEGDAELVLRLL
ERYDLHAFRLVNGRFATVVRTGDRVLLATDHAGSVPLYTCVAPGEVRAST
EAKALAAFPLADARRVAGLTGVYQVPAGAVMDIDLGSGTAVTHRTWTPGL
SRRILPEGEAVAAVRAALEKAVAQRVTPGDTPLVVLSGGIDSSGVAACAH
RAAGELDTVSMGTDTSNEFREARAVVDHLRTRHREITIPTTELLAQLPYA
VWASESVDPDIIEYLLPLTALYRALDGPERRILTGYGADIPLGGMHREDR
LPALDTVLAHDMATFDGLNEMSPVLSTLAGHWTTHPYWDREVLDLLVSLE
AGLKRRHGRDKWVLRAAMADALPAETVNRPKSSFSRLLLDHGVAEDRVHE
AKRQVVRELFDLTVGGGRHPSEVDTDDVVRSVADR
3D structure
PDB1mb9 The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots
ChainA
Resolution2.11 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A76 G77 D322 Y348 E382 K443
Catalytic site (residue number reindexed from 1) A70 G71 D310 Y336 E370 K431
Enzyme Commision number 6.3.3.4: (carboxyethyl)arginine beta-lactam-synthase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0034027 (carboxyethyl)arginine beta-lactam-synthase activity
GO:0046872 metal ion binding
Biological Process
GO:0006529 asparagine biosynthetic process
GO:0033050 clavulanic acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mb9, PDBe:1mb9, PDBj:1mb9
PDBsum1mb9
PubMed12409610
UniProtP0DJQ7|BLS_STRCL Carboxyethyl-arginine beta-lactam-synthase (Gene Name=bls)

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