Structure of PDB 1m8p Chain A

Receptor sequence
>1m8pA (length=573) Species: 5076 (Penicillium chrysogenum) [Search protein sequence]
MANAPHGGVLKDLLARDAPRQAELAAEAESLPAVTLTERQLCDLELIMNG
GFSPLEGFMNQADYDRVCEDNRLADGNVFSMPITLDASQEVIDEKKLQAA
SRITLRDFRDDRNLAILTIDDIYRPDKTKEAKLVFGGDPEHPAIVYLNNT
VKEFYIGGKIEAVNKLNHYDYVALRYTPAELRVHFDKLGWSRVVAFQTRN
PMHRAHRELTVRAARSRQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPR
YPNGMAVLGLLGLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGSN
SKGEDFYGPYDAQHAVEKYKDELGIEVVEFQMVTYLPDTDEYRPVDQVPA
GVKTLNISGTELRRRLRSGAHIPEWFSYPEVVKILRESNPPRATQGFTIF
LTGYMNSGKDAIARALQVTLNQQGGRSVSLLLGDTVRHELSSELGFTRED
RHTNIQRIAFVATELTRAGAAVIAAPIAPYEESRKFARDAVSQAGSFFLV
HVATPLEHCEQSDKRGIYAAARRGEIKGFTGVDDPYETPEKADLVVDFSK
QSVRSIVHEIILVLESQGFLERQ
3D structure
PDB1m8p Allosteric Inhibition via R-State Destabilization in ATP Sulfurylase from Penicillium chrysogenum
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T198 R199 H203 H206 R292
Catalytic site (residue number reindexed from 1) T198 R199 H203 H206 R292
Enzyme Commision number 2.7.7.4: sulfate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PPS A D434 R437 F446 R451 N454 I477 P479 R515 G528 F529 D434 R437 F446 R451 N454 I477 P479 R515 G528 F529
Gene Ontology
Molecular Function
GO:0004020 adenylylsulfate kinase activity
GO:0004781 sulfate adenylyltransferase (ATP) activity
GO:0005524 ATP binding
Biological Process
GO:0000103 sulfate assimilation

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Molecular Function
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Biological Process
External links
PDB RCSB:1m8p, PDBe:1m8p, PDBj:1m8p
PDBsum1m8p
PubMed12426581
UniProtQ12650|MET3_PENCH Sulfate adenylyltransferase (Gene Name=met3)

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