Structure of PDB 1m8k Chain A

Receptor sequence
>1m8kA (length=169) Species: 145262 (Methanothermobacter thermautotrophicus) [Search protein sequence]
TMRGLLVGRMQPFHRGALQVIKSILEEVDELIICIGSAQLSHSIRDPFTA
GERVMMLTKALSENGIPASRYYIIPVQDIECNALWVGHIKMLTPPFDRVY
SGNPLVQRLFSEDGYEVTAPPLFYRDRYSGTEVRRRMLDDGDWRSLLPES
VVEVIDEINGVERIKHLAK
3D structure
PDB1m8k Mutational, Structural, and Kinetic Studies of the ATP-binding Site of Methanobacterium thermoautotrophicum Nicotinamide Mononucleotide Adenylyltransferase
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.1: nicotinamide-nucleotide adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A V9 R11 V22 G38 S39 D80 I81 N84 W87 N105 L107 F125 Y126 V7 R9 V20 G36 S37 D78 I79 N82 W85 N103 L105 F123 Y124
Gene Ontology
Molecular Function
GO:0000309 nicotinamide-nucleotide adenylyltransferase activity
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009435 NAD biosynthetic process
GO:0019363 pyridine nucleotide biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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External links
PDB RCSB:1m8k, PDBe:1m8k, PDBj:1m8k
PDBsum1m8k
PubMed12810729
UniProtO26253|NADM_METTH Nicotinamide-nucleotide adenylyltransferase (Gene Name=MTH_150)

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