Structure of PDB 1m7b Chain A

Receptor sequence
>1m7bA (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRI
ELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEI
QEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGA
ATYIECSALQSENSVRDIFHVATLACVNK
3D structure
PDB1m7b Crystal structure of Rnd3/RhoE: functional implications
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T37 T55 T16 T34
BS02 GTP A S32 Q33 C34 G35 K36 T37 A38 F48 Y52 T55 K136 D138 L139 S178 L180 S11 Q12 C13 G14 K15 T16 A17 F27 Y31 T34 K115 D117 L118 S157 L159
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1m7b, PDBe:1m7b, PDBj:1m7b
PDBsum1m7b
PubMed12163169
UniProtP61587|RND3_HUMAN Rho-related GTP-binding protein RhoE (Gene Name=RND3)

[Back to BioLiP]