Structure of PDB 1m4n Chain A

Receptor sequence
>1m4nA (length=421) Species: 3750 (Malus domestica) [Search protein sequence]
LSRNATYFLGWQEYEKNPYHEVHNTNGIIQMGLAENQLCFDLLESWLAKN
PEAAAFKKNGESIFAELALFQDYHGLPAFKKAMVDFMAEIRGNKVTFDPN
HLVLTAGATSANETFIFCLADPGEAVLIPTPYYPGFDRDLKWRTGVEIVP
IHCTSSNGFQITETALEEAYQEAEKRNLRVKGVLVTNPSNPLGTTMTRNE
LYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVLKDRNCDENSEVW
QRVHVVYSLSKDLGLPGFRVGAIYSNDDMVVAAATKMSSFGLVSSQTQHL
LSAMLSDKKLTKNYIAENHKRLKQRQKKLVSGLQKSGISCLNGNAGLFCW
VDMRHLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHCTEPGWFRVCFAN
LPERTLDLAMQRLKAFVGEYY
3D structure
PDB1m4n Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding.
ChainA
Resolution2.01 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y145 D230 I232 K273
Catalytic site (residue number reindexed from 1) Y133 D218 I220 K261
Enzyme Commision number 1.4.-.-
4.4.1.14: 1-aminocyclopropane-1-carboxylate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A G119 A120 T121 Y145 D230 I232 Y233 S270 S272 K273 R281 G107 A108 T109 Y133 D218 I220 Y221 S258 S260 K261 R269
BS02 AAD A Y145 D151 Y133 D139
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0016491 oxidoreductase activity
GO:0016829 lyase activity
GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006520 amino acid metabolic process
GO:0009058 biosynthetic process
GO:0009693 ethylene biosynthetic process
GO:0009835 fruit ripening
GO:0042218 1-aminocyclopropane-1-carboxylate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1m4n, PDBe:1m4n, PDBj:1m4n
PDBsum1m4n
PubMed12686108
UniProtP37821|1A1C_MALDO 1-aminocyclopropane-1-carboxylate synthase (Gene Name=ACS-1)

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