Structure of PDB 1m05 Chain A

Receptor sequence
>1m05A (length=269) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFDTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAAPWIEQEGPE
YWDRNTQIFKTNTQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGR
LLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAARVAEQDRA
YLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEATLRCWALGF
YPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYT
CHVQHEGLPKPLTLRWEPS
3D structure
PDB1m05 The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 D9 Y59 N63 I66 N70 T73 D74 S77 N80 Y84 Y99 N114 Y116 Y123 T143 K146 W147 A150 V152 D156 Y159 W167 Y171 Y7 D9 Y51 N55 I58 N62 T65 D66 S69 N72 Y76 Y91 N106 Y108 Y115 T135 K138 W139 A142 V144 D148 Y151 W159 Y163
External links
PDB RCSB:1m05, PDBe:1m05, PDBj:1m05
PDBsum1m05
PubMed12391232
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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