Structure of PDB 1lxg Chain A

Receptor sequence
>1lxgA (length=71) Species: 8649 (Naja kaouthia) [Search protein sequence]
IRCFITPDITSKDCPNGHVCYTKTWCDAFCSIRGKRVDLGCAATCPTVKT
GVDIQCCSTDNCNPFPTRKRP
3D structure
PDB1lxg NMR-based Binding Screen and Structural Analysis of the Complex Formed between alpha-Cobratoxin and an 18-mer Cognate Peptide Derived from the alpha1 Subunit of the Nicotinic Acetylcholine Receptor from Torpedo californica
ChainA
ResolutionN/A
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D8 I9 T10 I32 R33 G34 K35 R36 R68 K69 D8 I9 T10 I32 R33 G34 K35 R36 R68 K69
Gene Ontology
Molecular Function
GO:0030550 acetylcholine receptor inhibitor activity
GO:0090729 toxin activity
GO:0099106 ion channel regulator activity
Biological Process
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1lxg, PDBe:1lxg, PDBj:1lxg
PDBsum1lxg
PubMed12133834
UniProtP01391|3L21_NAJKA Alpha-cobratoxin

[Back to BioLiP]