Structure of PDB 1lvk Chain A

Receptor sequence
>1lvkA (length=743) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECGE
IVSETSDSFTFKTSDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPA
VFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEV
APHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG
RNQAGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNNAGFIS
GASIQSYLLEKSRVVFQSTSERNYHIFYQLLAGATAEEKKALHLAGPESF
NYLNQSGCVDIKGVSDEDEFKITRQAMDIVGFSQEEQMSIFKIIAGILHL
GNIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDL
VAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCSERKAYFIGVLD
ISGFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKVEQEKYLKEKINLDSQ
ATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEP
RFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKL
FNDPNIASRAFLTVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAK
LEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYDLAPNVPRDA
EDSQKATDAVLKHLNIDPEQFRFGITKIFFRAGQLARIEEARE
3D structure
PDB1lvk X-ray crystal structure and solution fluorescence characterization of Mg.2'(3')-O-(N-methylanthraniloyl) nucleotides bound to the Dictyostelium discoideum myosin motor domain.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S180 G181 T185 N229 S232 S233 G453 E455
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T186 S237 T185 S233
BS02 MNT A N127 P128 S181 G182 G184 K185 T186 E187 N233 N234 N235 N126 P127 S180 G181 G183 K184 T185 E186 N229 N230 N231 PDBbind-CN: -logKd/Ki=5.92,Kd=1.2uM
BS03 BEF A S181 K185 N233 S236 S237 S180 K184 N229 S232 S233
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1lvk, PDBe:1lvk, PDBj:1lvk
PDBsum1lvk
PubMed9405148
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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