Structure of PDB 1lvb Chain A

Receptor sequence
>1lvbA (length=214) Species: 12227 (Tobacco etch virus) [Search protein sequence]
PRDYNPISSTICHLTNESDGHTTSLYGIGFGPFIITNKHLFRRNNGTLLV
QSLHGVFKVKNTTTLQQHLIDGRDMIIIRMPKDFPPFPQKLKFREPQREE
RICLVTTNFQTKSMSSMVSDTSCTFPSSDGIFWKHWIQTKDGQAGSPLVS
TRDGFIVGIHSASNFTNTNNYFTSVPKNFMELLTNQEAQQWVSGWRLNAD
SVLWGGHKVFMSKP
3D structure
PDB1lvb Structural basis for the substrate specificity of tobacco etch virus protease.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.-.-
3.4.22.44: nuclear-inclusion-a endopeptidase.
3.4.22.45: helper-component proteinase.
3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A T29 S31 H46 D81 T146 D148 G149 A151 H167 S168 A169 S170 N171 N174 N176 Y178 W211 G213 H214 K215 V216 F217 M218 K220 T22 S24 H39 D74 T139 D141 G142 A144 H160 S161 A162 S163 N164 N167 N169 Y171 W204 G206 H207 K208 V209 F210 M211 K213
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1lvb, PDBe:1lvb, PDBj:1lvb
PDBsum1lvb
PubMed12377789
UniProtP04517|POLG_TEV Genome polyprotein

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