Structure of PDB 1lv0 Chain A

Receptor sequence
>1lv0A (length=433) Species: 9913 (Bos taurus) [Search protein sequence]
HHMDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITP
LEELYKRFQLLEGPPETMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTR
YLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVA
NFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYL
DQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGT
YMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVI
RIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGK
YIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQV
FCSCSYDATTHFETTCNDIKDIYKRMAGSAFDF
3D structure
PDB1lv0 Geranylgeranyl switching regulates GDI-Rab GTPase recycling.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GER A V25 Y93 D430 V27 Y95 D432
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005093 Rab GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
Biological Process
GO:0007264 small GTPase-mediated signal transduction
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0032482 Rab protein signal transduction
GO:0050771 negative regulation of axonogenesis
GO:0090315 negative regulation of protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:1lv0, PDBe:1lv0, PDBj:1lv0
PDBsum1lv0
PubMed12623022
UniProtP21856|GDIA_BOVIN Rab GDP dissociation inhibitor alpha (Gene Name=GDI1)

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