Structure of PDB 1lua Chain A

Receptor sequence
>1luaA (length=287) Species: 272630 (Methylorubrum extorquens AM1) [Search protein sequence]
SKKLLFQFDTDATPSVFDVVVGYDGGADHITGYGNVTPDNVGAYVDGTIY
TRGGKEKQSTAIFVGGGDMAAGERVFEAVKKRFFGPFRVSCMLDSNGSNT
TAAAGVALVVKAAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCG
RKLDKAQAAADSVNKRFKVNVTAAETADDASRAEAVKGAHFVFTAGAIGL
ELLPQAAWQNESSIEIVADYNAQPPLGIGGIDATDKGKEYGGKRAFGALG
IGGLKLKLHRACIAKLFESSEGVFDAEEIYKLAKEMA
3D structure
PDB1lua Structure of methylene-tetrahydromethanopterin dehydrogenase from methylobacterium extorquens AM1.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.5.1.-
1.5.1.5: methylenetetrahydrofolate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A N97 T102 A127 T129 G130 P131 V132 R152 K156 G197 A198 I199 L201 Y221 K256 N96 T101 A126 T128 G129 P130 V131 R151 K155 G196 A197 I198 L200 Y220 K255
Gene Ontology
Molecular Function
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006730 one-carbon metabolic process
GO:0046294 formaldehyde catabolic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:1lua, PDBe:1lua, PDBj:1lua
PDBsum1lua
PubMed12176390
UniProtP55818|MTDA_METEA Bifunctional protein MdtA (Gene Name=mtdA)

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