Structure of PDB 1lrr Chain A

Receptor sequence
>1lrrA (length=118) Species: 562 (Escherichia coli) [Search protein sequence]
TIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLDAQAFAEATESL
HGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMIEHI
MQSMQFPAELIEKVCGTI
3D structure
PDB1lrr Insights into negative modulation of E. coli replication initiation from the structure of SeqA-hemimethylated DNA complex
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A G115 R116 T117 R118 Y120 N133 Q134 N150 R155 G52 R53 T54 R55 Y57 N70 Q71 N87 R92 PDBbind-CN: Kd=7uM
BS02 dna A R86 A87 V88 R116 K138 N152 T153 R23 A24 V25 R53 K75 N89 T90 PDBbind-CN: Kd=7uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:1lrr, PDBe:1lrr, PDBj:1lrr
PDBsum1lrr
PubMed12379844
UniProtP0AFY8|SEQA_ECOLI Negative modulator of initiation of replication (Gene Name=seqA)

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