Structure of PDB 1lkk Chain A

Receptor sequence
>1lkkA (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
LEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFD
QNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLS
RPCQT
3D structure
PDB1lkk Crystal structures of the human p56lck SH2 domain in complex with two short phosphotyrosyl peptides at 1.0 A and 1.8 A resolution.
ChainA
Resolution1.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R134 R154 S156 E157 S158 S164 H180 Y181 K182 R196 G215 R13 R33 S35 E36 S37 S43 H59 Y60 K61 R75 G94
External links
PDB RCSB:1lkk, PDBe:1lkk, PDBj:1lkk
PDBsum1lkk
PubMed8604142
UniProtP06239|LCK_HUMAN Tyrosine-protein kinase Lck (Gene Name=LCK)

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