Structure of PDB 1lhv Chain A

Receptor sequence
>1lhvA (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
PPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNP
KDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSV
LLEVDGEEVLRLRQVSGPLHPIMRIALGGLLFPASNLRLPLVPALDGCLR
RDSWLDKQAEISASAPTSLRSCD
3D structure
PDB1lhv Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D50 E52 A160 D38 E40 A144
BS02 ZN A D65 H83 H136 D53 H71 H120
BS03 NOG A S41 S42 D65 F67 N82 V105 M107 M139 L171 S29 S30 D53 F55 N70 V93 M95 M123 L155 PDBbind-CN: -logKd/Ki=8.91,Kd=1.23nM
BindingDB: Kd=1.2nM
External links
PDB RCSB:1lhv, PDBe:1lhv, PDBj:1lhv
PDBsum1lhv
PubMed12065592
UniProtP04278|SHBG_HUMAN Sex hormone-binding globulin (Gene Name=SHBG)

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