Structure of PDB 1le5 Chain A

Receptor sequence
>1le5A (length=274) Species: 10090 (Mus musculus) [Search protein sequence]
MAYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYT
GPGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLG
IQCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRD
PAGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCD
KVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVR
VSMQLRRPSDRELSEPMEFQYLPD
3D structure
PDB1le5 The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the Interferon beta-kB site
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R35 Y36 C38 E39 K122 R187 P189 K221 R246 Q247 R18 Y19 C21 E22 K105 R170 P172 K204 R229 Q230
BS02 dna A R33 A43 G44 R16 A26 G27
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1le5, PDBe:1le5, PDBj:1le5
PDBsum1le5
PubMed11970948
UniProtQ04207|TF65_MOUSE Transcription factor p65 (Gene Name=Rela)

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