Structure of PDB 1ldb Chain A

Receptor sequence
>1ldbA (length=294) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
MKNNGGARVVVIGAGFVGASYVFALMNQGIADEIVLIDANESKAIGDAMD
FNHGKVFAPKPVDIWDYDDCRDADLVVICAGANDLVDKNIAIFRSIVESV
MASGFQGLFLVATNPVDILTYATWKFSGLPHERVIGSGTILDTARFRFLL
GEYFSVAPQNVHAYIIGEHGDTELPVWSQAYIGVMPIDLERIFVNVRDAA
YQIIEKKGATYYGIAMGLARVTRAILHNENAILTVSAYLDGLYGERDVYI
GVPAVINRNGIREVIEIELNDDEKNRFHHSAATLKSVLARAFTR
3D structure
PDB1ldb Structure determination and refinement of Bacillus stearothermophilus lactate dehydrogenase.
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D166 R169 H193
Catalytic site (residue number reindexed from 1) D142 R145 H169
Enzyme Commision number 1.1.1.27: L-lactate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A R169 H193 T247 R145 H169 T210
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004459 L-lactate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding
Biological Process
GO:0006089 lactate metabolic process
GO:0006090 pyruvate metabolic process
GO:0006096 glycolytic process
GO:0019752 carboxylic acid metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ldb, PDBe:1ldb, PDBj:1ldb
PDBsum1ldb
PubMed2330370
UniProtP00344|LDH_GEOSE L-lactate dehydrogenase (Gene Name=ldh)

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