Structure of PDB 1lcj Chain A

Receptor sequence
>1lcjA (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQ
NQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSR
PCQT
3D structure
PDB1lcj Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R134 R154 S156 E157 S158 S164 H180 Y181 K182 R196 G215 R12 R32 S34 E35 S36 S42 H58 Y59 K60 R74 G93
External links
PDB RCSB:1lcj, PDBe:1lcj, PDBj:1lcj
PDBsum1lcj
PubMed7680435
UniProtP06239|LCK_HUMAN Tyrosine-protein kinase Lck (Gene Name=LCK)

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