Structure of PDB 1lbh Chain A

Receptor sequence
>1lbhA (length=296) Species: 562 (Escherichia coli) [Search protein sequence]
LLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKTAV
HNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQTPINSIIF
SHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQ
PIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESG
LRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQ
AVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRLE
3D structure
PDB1lbh Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IPT A S69 A75 I79 R197 W220 D274 S8 A14 I18 R136 W159 D213
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042802 identical protein binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1lbh, PDBe:1lbh, PDBj:1lbh
PDBsum1lbh
PubMed8638105
UniProtP03023|LACI_ECOLI Lactose operon repressor (Gene Name=lacI)

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