Structure of PDB 1lb8 Chain A

Receptor sequence
>1lb8A (length=261) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKY
KLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVID
FSKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSK
IAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIE
QRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLK
NKWWYDKGECG
3D structure
PDB1lb8 Mechanism of glutamate receptor desensitization.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMQ A Y61 T91 R96 G141 S142 T143 E193 Y60 T90 R95 G140 S141 T142 E192 BindingDB: Ki=17nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1lb8, PDBe:1lb8, PDBj:1lb8
PDBsum1lb8
PubMed12015593
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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