Structure of PDB 1l6o Chain A

Receptor sequence
>1l6oA (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence]
MIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEP
GDMLLQVNDINFENMSNDDAVRVLRDIVHKPGPIVLTVAKLEHHH
3D structure
PDB1l6o Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A L265 G266 I267 I269 V270 G271 S273 R325 L15 G16 I17 I19 V20 G21 S23 R75
BS02 peptide A Q272 Y282 L341 E342 H343 H345 Q22 Y32 L91 E92 H93 H95
Gene Ontology
Biological Process
GO:0016055 Wnt signaling pathway

View graph for
Biological Process
External links
PDB RCSB:1l6o, PDBe:1l6o, PDBj:1l6o
PDBsum1l6o
PubMed11970895
UniProtP51142|DVL2_XENLA Segment polarity protein dishevelled homolog DVL-2 (Gene Name=dvl2)

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