Structure of PDB 1l2o Chain A

Receptor sequence
>1l2oA (length=777) Species: 31199 (Argopecten irradians) [Search protein sequence]
FSDPDFQYLAVDRKKLMKAFDGKKNCWVPDEKEGFASAEIQSSKGDEITV
KIVADSSTRTVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRYT
SGLIYTYSGLFCIAVNPYRRLPIYTDSVIAKYRGKRKTEIPPHLFSVADN
AYQNMVTDRENQSCLITGESGAGKTENTKKVIMYLAKVACAVKEGSLEDQ
IIQANPVLEAYGNAKTTRNNNSSRFGKFIRIHFGPTGKIAGADIETYLLE
KSRVTYQQSAERNYHIFYQICSNAIPELNDVMLVTPDSGLYSFINQGCLT
VDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASILHMGEMKFQAESD
GTAEAEKVAFLCGINAGDLLKALLKPKVTEMVTKGQNMNQVVNSVGALAK
SLYDRMFNWLVRRVNKTLDTKAKRNYYIGVLDIAGFEIFDFNSFEQLCIN
YTNERLQQFFNHHMFILEQEEYKKEGIAWEFIDFGMDLQMCIDLIEKPMG
ILSILEEECMFPKADDKSFQDKLYQNHMGKNRMFTKPGKRPNQGPAHFEL
HHYAGNVPYSITGWLEKNKDPINENVVALLGASKEPLVAELFKAFQTISA
VHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQCNGVL
RKGFPSRLIYSEFKQRYSILAPNAIDGKTVSEKILAGLQMDPAEYRLGTT
KVFFKAGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQRIGL
SVIQRNIRKWLVLRNWQWWKLYSKVKP
3D structure
PDB1l2o Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor.
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S178 G179 T183 N237 S240 S241 G463 E465
Catalytic site (residue number reindexed from 1) S170 G171 T175 N219 S222 S223 G435 E437
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T183 S241 T175 S223
BS02 PDM A Q485 Y583 C693 K705 Q457 Y553 C646 K652
BS03 ADP A N124 P125 Y126 R127 G179 G181 K182 T183 E184 N237 N116 P117 Y118 R119 G171 G173 K174 T175 E176 N219
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1l2o, PDBe:1l2o, PDBj:1l2o
PDBsum1l2o
PubMed12297624
UniProtP24733|MYS_ARGIR Myosin heavy chain, striated muscle

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