Structure of PDB 1l1r Chain A

Receptor sequence
>1l1rA (length=179) Species: 5741 (Giardia intestinalis) [Search protein sequence]
TMSVADAHALIKTIPDFPTKGIAFKDLSDILSTPAALDAVRKEVTAHYKD
VPITKVVGIESRGFILGGIVANSLGVGFVALRKAGKLPGDVCKCTFDMEY
QKGVTIEVQKRQLGPHDVVLLHDDVLATGGTLLAAIELCETAGVKPENIY
INVLYEIEALKGREKVGQKCTRLFSVIRE
3D structure
PDB1l1r Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration.
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R63 E100
Catalytic site (residue number reindexed from 1) R62 E99
Enzyme Commision number 2.4.2.7: adenine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9DA A F25 K26 R63 E100 Y101 F24 K25 R62 E99 Y100
BS02 PRP A S62 R63 M99 Y101 D124 D125 V126 A128 T129 G130 T132 S61 R62 M98 Y100 D123 D124 V125 A127 T128 G129 T131
Gene Ontology
Molecular Function
GO:0003999 adenine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1l1r, PDBe:1l1r, PDBj:1l1r
PDBsum1l1r
PubMed12171925
UniProtQ967M2

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