Structure of PDB 1kyv Chain A

Receptor sequence
>1kyvA (length=147) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
DLKGPELRILIVHARWNLQAIEPLVKGAVETMIEKHDVKLENIDIESVPG
SWELPQGIRASIARNTYDAVIGIGVLIKGSTMHFEYISEAVVHGLMRVGL
DSGVPVILGLLTVLNEEQALYRAGLNGGHNHGNDWGSAAVEMGLKAL
3D structure
PDB1kyv The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H94
Catalytic site (residue number reindexed from 1) H83
Enzyme Commision number 2.5.1.78: 6,7-dimethyl-8-ribityllumazine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RBF A W27 G61 S62 W63 E64 V86 L87 H94 W16 G50 S51 W52 E53 V75 L76 H83 MOAD: Kd=1.2uM
BS02 RBF A I118 L119 H142 W146 I107 L108 H131 W135 MOAD: Kd=1.2uM
Gene Ontology
Molecular Function
GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity
GO:0004746 riboflavin synthase activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:1902444 riboflavin binding
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005758 mitochondrial intermembrane space
GO:0009349 riboflavin synthase complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1kyv, PDBe:1kyv, PDBj:1kyv
PDBsum1kyv
PubMed12083520
UniProtQ9UUB1|RIB4_SCHPO 6,7-dimethyl-8-ribityllumazine synthase (Gene Name=rib4)

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