Structure of PDB 1kwo Chain A

Receptor sequence
>1kwoA (length=780) Species: 31199 (Argopecten irradians) [Search protein sequence]
FSDPDFQYLAVDRKKLMKEAFDGKKNCWVPDEKEGFASAEIQSSKGDEIT
VKIVADSSTRTVKKDDIQSMNPPKFEKLEDMANMTYLNEASVLYNLRSRY
TSGLIYTYSGLFCIAVNPYRRLPIYTDSVIAKYRGKRKTEIPPHLFSVAD
NAYQNMVTDRENQSCLITGESGAGKTENTKKVIMYLAKVACAVKKEGSLE
DQIIQANPVLEAYGNAKTTRNNNSSRFGKFIRIHFGPTGKIAGADIETYL
LEKSRVTYQQSAERNYHIFYQICSNAIPELNDVMLVTPDSGLYSFINQGC
LTVDNIDDVEEFKLCDEAFDILGFTKEEKQSMFKCTASILHMGEMKFKQR
PREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGVTKGQNMNQV
VNSVGALAKSLYDRMFNWLVRRVNKTLDTKAKRNYYIGVLDIAGFEIFDF
NSFEQLCINYTNERLQQFFNHHMFILEQEEYKKEGIAWEFIDFGMDLQMC
IDLIEKPMGILSILEEECMFPKADDKSFQDKLYQNHMGKNRMFTRPNQGP
AHFELHHYAGNVPYSITGWLEKNKDPINENVVALLGASKEPLVAELFKAF
QTISAVHRESLNKLMKNLYSTHPHFVRCIIPNELKQPGLVDAELVLHQLQ
CNGVLRKGFPSRLIYSEFKQRYSILAPNDGKTVSEKILAGLQMDPAEYRL
GTTKVFFKAGVLGNLEEMRDERLSKIISMFQAHIRGYLIRKAYKKLQDQR
IGLSVIQRNIRKWLVLRNWQWWKLYSKVKP
3D structure
PDB1kwo Crystallographic findings on the internally uncoupled and near-rigor states of myosin: Further insights into the mechanics of the motor
ChainA
Resolution3.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S178 G179 T183 N237 S240 S241 G463 E465
Catalytic site (residue number reindexed from 1) S171 G172 T176 N221 S224 S225 G444 E446
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T183 S241 T176 S225
BS02 AGS A N124 P125 Y126 S178 G179 G181 K182 T183 E184 S241 N117 P118 Y119 S171 G172 G174 K175 T176 E177 S225
BS03 PDM A A584 Q692 C693 K705 A559 Q650 C651 K657
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1kwo, PDBe:1kwo, PDBj:1kwo
PDBsum1kwo
PubMed12297624
UniProtP24733|MYS_ARGIR Myosin heavy chain, striated muscle

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