Structure of PDB 1kwf Chain A

Receptor sequence
>1kwfA (length=363) Species: 1515 (Acetivibrio thermocellus) [Search protein sequence]
AGVPFNTKYPYGPTSIADNQSEVTAMLKAEWEDWKSKRITSNGAGGYKRV
QRDASTNYDTVSQGMGYGLLLAVCFNEQALFDDLYRYVKSHFNGNGLMHW
HIDANNNVTSHDGGDGAATDADEDIALALIFADKLWGSSGAINYGQEART
LINNLYNHCVEHGSYVLKPGDRWGGSSVTNPSYFAPAWYKVYAQYTGDTR
WNQVADKCYQIVEEVKKYNNGTGLVPDWCTASGTPASGQSYDYKYDATRY
GWRTAVDYSWFGDQRAKANCDMLTKFFARDGAKGIVDGYTIQGSKISNNH
NASFIGPVAAASMTGYDLNFAKELYRETVAVKDSEYYGYYGNSLRLLTLL
YITGNFPNPLSDL
3D structure
PDB1kwf Atomic (0.94 A) resolution structure of an inverting glycosidase in complex with substrate.
ChainA
Resolution0.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A R84 Q95 Y277 D278 Y372 R52 Q63 Y245 D246 Y340
BS02 BGC A V93 Q95 W132 D152 R281 V61 Q63 W100 D120 R249
BS03 BGC A W132 A149 A150 W100 A117 A118
BS04 BGC A G145 R204 W205 G113 R172 W173
BS05 BGC A Q95 Y371 Y372 Q63 Y339 Y340
BS06 BGC A Y277 Y369 Y245 Y337
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1kwf, PDBe:1kwf, PDBj:1kwf
PDBsum1kwf
PubMed11884144
UniProtA3DC29|GUNA_ACET2 Endoglucanase A (Gene Name=celA)

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