Structure of PDB 1kuk Chain A

Receptor sequence
>1kukA (length=201) Species: 103944 (Protobothrops mucrosquamatus) [Search protein sequence]
QRFPQRYIELAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIA
ITLALLDVWSEKDFITVQADAPTTAGLFGDWRERVLLKKKNHDHAQLLTD
TNFARNTIGWAYVGRMCDEKYSVAVVKDHSSKVFMVAVTMTHELGHNLGM
EHDDKDKCKCDTCIMSAVISDKQSKLFSDCSKDYYQTFLTNDNPQCILNA
P
3D structure
PDB1kuk Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues.
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R107 N108 T109 I110 T141 H144 E145 H154 I166 S168 A169 V170 I171 R105 N106 T107 I108 T139 H142 E143 H152 I164 S166 A167 V168 I169
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1kuk, PDBe:1kuk, PDBj:1kuk
PDBsum1kuk
PubMed12071970
UniProtO57413|VM2T3_PROMU Zinc metalloproteinase/disintegrin

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