Structure of PDB 1kpl Chain A

Receptor sequence
>1kplA (length=430) [Search protein sequence]
TPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWP
LAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPV
KFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLAT
GAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFR
IFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGVVGPVFNSLVLRTQDMF
QRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSV
GLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFP
QYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCL
GATLLAQFLGGKPLYSTILARTLAKQDAEQ
3D structure
PDB1kpl X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CL A S107 F357 S77 F327
Gene Ontology
Molecular Function
GO:0005247 voltage-gated chloride channel activity
GO:0015108 chloride transmembrane transporter activity
GO:0015297 antiporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006821 chloride transport
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1kpl, PDBe:1kpl, PDBj:1kpl
PDBsum1kpl
PubMed11796999
UniProtQ8ZRP8|CLCA_SALTY H(+)/Cl(-) exchange transporter ClcA (Gene Name=clcA)

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