Structure of PDB 1kpi Chain A

Receptor sequence
>1kpiA (length=291) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERPDMTLEEAQYAKR
KLALDKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHD
KAMFDEVDSPRRKEVRIQGWEEFDEPVDRIVSLGAFEHFADGAGDAGFER
YDTFFKKFYNLTPDDGRMLLHTITIPDKEEAQELGLTSPMSLLRFIKFIL
TEIFPGGRLPRISQVDYYSSNAGWKVERYHRIGANYVPTLNAWADALQAH
KDEAIALKGQETCDIYMHYLRGCSDLFRDKYTDVCQFTLVK
3D structure
PDB1kpi Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis
ChainA
Resolution2.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.79: cyclopropane-fatty-acyl-phospholipid synthase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008825 cyclopropane-fatty-acyl-phospholipid synthase activity
Biological Process
GO:0001666 response to hypoxia
GO:0006629 lipid metabolic process
GO:0008610 lipid biosynthetic process
GO:0032259 methylation
GO:0046500 S-adenosylmethionine metabolic process
GO:0052167 symbiont-mediated perturbation of host innate immune response
GO:0071766 Actinobacterium-type cell wall biogenesis
GO:0071768 mycolic acid biosynthetic process
GO:0071769 mycolate cell wall layer assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1kpi, PDBe:1kpi, PDBj:1kpi
PDBsum1kpi
PubMed11756461
UniProtP9WPB5|CMAS2_MYCTU Cyclopropane mycolic acid synthase 2 (Gene Name=cmaA2)

[Back to BioLiP]