Structure of PDB 1kjr Chain A

Receptor sequence
>1kjrA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB1kjr Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A H158 R162 W181 E184 H46 R50 W69 E72 PDBbind-CN: -logKd/Ki=6.06,Kd=0.88uM
BS02 BEK A R144 H158 N160 R32 H46 N48 PDBbind-CN: -logKd/Ki=6.06,Kd=0.88uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:1kjr, PDBe:1kjr, PDBj:1kjr
PDBsum1kjr
PubMed15701008
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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