Structure of PDB 1kfg Chain A

Receptor sequence
>1kfgA (length=612) Species: 1521 (Ruminiclostridium cellulolyticum) [Search protein sequence]
TYNYGEALQKSIMFYEFQRSGDLPADKRDNWRDDSGMKDGSDVGVDLTGG
WYDAGDHVKFNLPMSYTSAMLAWSLYEDKDAYDKSGQTKYIMDGIKWAND
YFIKCNPTPGVYYYQVGDGGKDHSWWGPAEVMQMERPSFKVDASKPGSAV
CASTAASLASAAVVFKSSDPTYAEKCISHAKNLFDMADKAKSDAGYTAAS
GYYSSSSFYDDLSWAAVWLYLATNDSTYLDKAESYVPNWGKEQQTDIIAY
KWGQCWDDVHYGAELLLAKLTNKQLYKDSIEMNLDFWTTGVNGTRVSYTP
KGLAWLFQWGSLRHATTQAFLAGVYAEWEGCTPSKVSVYKDFLKSQIDYA
LGSTGRSFVVGYGVNPPQHPHHRTAHGSWTDQMTSPTYHRHTIYGALVGG
PDNADGYTDEINNYVNNEIACDYNAGFTGALAKMYKHSGGDPIPNFKAIE
KITNDEVIIKAGLNSTGPNYTEIKAVVYNQTGWPARVTDKISFKYFMDLS
EIVAAGIDPLSLVTSSNYSEGKNTKVSGVLPWDVSNNVYYVNVDLTGENI
YPGGQSACRREVQFRIAAPQGTTYWNPKNDFSYDGLPTTSTVNTVTNIPV
YDNGVKVFGNEP
3D structure
PDB1kfg The X-ray crystal structure of the multidomain endoglucanase Cel9G from Clostridium cellulolyticum complexed with natural and synthetic cello-olligosaccharides
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D55 D58 Y205 E420
Catalytic site (residue number reindexed from 1) D53 D56 Y203 E418
Enzyme Commision number 3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GS1 A H125 Y204 Y205 E420 Y425 H123 Y202 Y203 E418 Y423
BS02 SGC A W258 W311 R315 W256 W309 R313
BS03 BGC A W254 C257 D259 W252 C255 D257
BS04 SGC A W254 D259 W252 D257
BS05 CA A D500 E503 N578 N581 D582 D498 E501 N576 N579 D580
BS06 CA A S209 D212 D213 D259 S207 D210 D211 D257
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0030246 carbohydrate binding
GO:0030248 cellulose binding
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1kfg, PDBe:1kfg, PDBj:1kfg
PDBsum1kfg
PubMed12837787
UniProtP37700|GUNG_RUMCH Endoglucanase G (Gene Name=celCCG)

[Back to BioLiP]