Structure of PDB 1kdx Chain A

Receptor sequence
>1kdxA (length=81) Species: 10090 (Mus musculus) [Search protein sequence]
GVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKV
EGDMYESANSRDEYYHLLAEKIYKIQKELEE
3D structure
PDB1kdx Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions.
ChainA
ResolutionN/A
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L599 H602 L603 K606 Y650 H651 A654 E655 Y658 L14 H17 L18 K21 Y65 H66 A69 E70 Y73
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1kdx, PDBe:1kdx, PDBj:1kdx
PDBsum1kdx
PubMed9413984
UniProtP45481|CBP_MOUSE Histone lysine acetyltransferase CREBBP (Gene Name=Crebbp)

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