Structure of PDB 1kdk Chain A

Receptor sequence
>1kdkA (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
DPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTN
PKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDS
VLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASNLRLPLVPAL
DGCLRRDSWLDKQAEISASAPTSLRSC
3D structure
PDB1kdk Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site.
ChainA
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DHT A S41 S42 D65 F67 N82 L171 S30 S31 D54 F56 N71 L160 MOAD: Kd=0.9nM
PDBbind-CN: -logKd/Ki=9.05,Kd=0.9nM
BindingDB: IC50=3.8nM,Kd=0.182000nM
External links
PDB RCSB:1kdk, PDBe:1kdk, PDBj:1kdk
PDBsum1kdk
PubMed12054810
UniProtP04278|SHBG_HUMAN Sex hormone-binding globulin (Gene Name=SHBG)

[Back to BioLiP]