Structure of PDB 1kc2 Chain A

Receptor sequence
>1kc2A (length=96) Species: 11886 (Rous sarcoma virus) [Search protein sequence]
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSLNVAH
YKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
3D structure
PDB1kc2 Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R157 R177 E180 T181 H203 Y204 K205 R219 G238 R11 R31 E34 T35 H50 Y51 K52 R66 G85
External links
PDB RCSB:1kc2, PDBe:1kc2, PDBj:1kc2
PDBsum1kc2
PubMed11851339
UniProtP00524|SRC_RSVSA Tyrosine-protein kinase transforming protein Src (Gene Name=V-SRC)

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