Structure of PDB 1k6x Chain A

Receptor sequence
>1k6xA (length=324) Species: 162425 (Aspergillus nidulans) [Search protein sequence]
QQKKTIAVVNATGRQAASLIRVAAAVGHHVRAQVHSLKGLIAEELQAIPN
VTLFQGPLLNNVPLMDTLFEGAHLAFINTTSQAGDEIAIGKDLADAAKRA
GTIQHYIYSSMPDHSLYGPWPAVPMWAPKFTVENYVRQLGLPSTFVYAGI
YNNNFTSLPYPLFQMELMPDGTFEWHAPFDPDIPLPWLDAEHDVGPALLQ
IFKDGPQKWNGHRIALTFETLSPVQVCAAFSRALNRRVTYVQVPKVEIKV
NIPVGYREQLEAIEVVFGEHKAPYFPLPEFSGGVISQRVTDEARKLWSGW
RDMEEYAREVFPIEEEANGLDWML
3D structure
PDB1k6x The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G15 R16 Q17 H37 N80 Q84 M113 K131 A150 I152 Y153 N156 Y276 G13 R14 Q15 H35 N78 Q82 M111 K129 A148 I150 Y151 N154 Y274
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0051287 NAD binding
GO:0070401 NADP+ binding
GO:0070402 NADPH binding
GO:0070403 NAD+ binding
GO:0070404 NADH binding
GO:0070405 ammonium ion binding
GO:0070406 glutamine binding
Biological Process
GO:0001081 nitrogen catabolite repression of transcription from RNA polymerase II promoter
GO:0006808 regulation of nitrogen utilization
GO:0045892 negative regulation of DNA-templated transcription
GO:0090295 nitrogen catabolite repression of transcription
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1k6x, PDBe:1k6x, PDBj:1k6x
PDBsum1k6x
PubMed11726498
UniProtQ5AU62|NMRA_EMENI Nitrogen metabolite repression protein nmrA (Gene Name=nmrA)

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