Structure of PDB 1k4w Chain A

Receptor sequence
>1k4wA (length=244) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TMSEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREA
LWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRM
CRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEE
EIALFSSAVLISPDRAWLLEPRKVQKLQEKIYFALQHVIQKNHLDDETLA
KLIAKIPTITAVCNLHGEKLQVFKQSHPDIVNTLFPPLYKELFN
3D structure
PDB1k4w X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K278 Q288 I292 P444 L445 E448 K71 Q81 I85 P237 L238 E241
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:1k4w, PDBe:1k4w, PDBj:1k4w
PDBsum1k4w
PubMed11689423
UniProtP45446|RORB_RAT Nuclear receptor ROR-beta (Gene Name=Rorb)

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