Structure of PDB 1k4i Chain A

Receptor sequence
>1k4iA (length=216) Species: 148305 (Pyricularia grisea) [Search protein sequence]
FDAIPDVIQAFKNGEFVVVLDDPSRENEADLIIAAESVTTEQMAFMVRHS
SGLICAPLTPERTTALDLPQMVTHNADPRGTAYTVSVDAEHPSTTTGISA
HDRALACRMLAAPDAQPSHFRRPGHVFPLRAVAGGVRARRGHTEAGVELC
RLAGKRPVAVISEIVDDGQEVEGRAVRAAPGMLRGDECVAFARRWGLKVC
TIEDMIAHVEKTEGKL
3D structure
PDB1k4i Structural definition of the active site and catalytic mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase.
ChainA
Resolution0.98 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E37 D41 C66 R90 Y94 D99 H136 H153 E174
Catalytic site (residue number reindexed from 1) E26 D30 C55 R79 Y83 D88 H125 H142 E163
Enzyme Commision number 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A R36 R150 G152 H153 T154 R25 R139 G141 H142 T143
BS02 SO4 A Q81 R141 Q70 R130
BS03 MG A E37 H153 E26 H142
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1k4i, PDBe:1k4i, PDBj:1k4i
PDBsum1k4i
PubMed11827524
UniProtQ8TG90|RIB3_PYRO7 3,4-dihydroxy-2-butanone 4-phosphate synthase (Gene Name=RIB3)

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